Hyperglycemic coma

Epinephrine is used for relieving bronchial asthma, revival from anaphylactic shock, in hyperglycemic coma, and allergic reactions. It is used as a local vasoconstrictor, in particular, in ophthalmology for reducing intraocular pressure. 

Variations in Dosage Form Insulin solution. Dissolved insulin is dispensed as a clear neutral solution known as regular (R) insulin or crystalline zinc insulin. In emergencies, such as hyperglycemic coma,... 

When hyperglycemic coma occurs it is almost always of the hyperosmolar nonketotic type. After termination... 

Acute angle closure glaucoma has been reported as rare complication of rapid insulin therapy for hyperglycemic non-ketotic coma (20). It was postulated that raised glucose concentrations in the lens leads to increased sorbitol and water influx. The osmotic changes in the lens are not immediately corrected when the glucose concentration in aqueous humor is lowered, and this can lead to obstruction of the canal of Schlemm and increased intraocular pressure. 

Roefaro J, Mukherjee SM. Olanzapine-induced hyperglycemic nonketonic coma. Ann Pharmacother 2001 35(3) 300-2. 

Assess the client for hyperosmolar, hyperglycemic, nonketotic coma. 

A client with Type 1 diabetes will experience diabetic ketoacidosis a client with Type 2 diabetes will experience hyperosmolar, hyperglycemic, nonketotic coma. 

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