2- 2-hydroxymethyl-1,3-propanediol

The main intermediates in the pentaerythritol production reaction have been identified and synthesized (50,51) and the intermediate reaction mechanisms deduced. Without adequate reaction control, by-product formation can easily occur (52,53). Generally mild reaction conditions are favored for optimum results (1,54). However, formation of by-products caimot be entirely eliminated, particularly dipentaerytbritol and the linear formal of pentaerythritol, 2,2 -[meth5lenebis(oxymethylene)]bis(2-hydroxymethyl-1,3-propanediol) [6228-26-8] ... 

Chemical Name 2-Amino-2-hydroxymethyl-1,3-propanediol Common Name Trometamol Structural Formula ... 

A demulsifier composition that is a blend of (1) a propoxylated-ethoxylated block copolymer of a bis-hydroxyalkyl ether and (2) a propoxylated-ethoxylated block copolymer of 2-hydroxymethyl-1,3-propanediol has been described [1750,1751]. 

The blend is partially crosslinked with a vinyl monomer when dissolved in an organic aprotic solvent and has a pH of 5.0 or lower. The first block copolymer is prepared by polycondensing a bis-hydroxyalkyl ether, such as dipropylene glycol, diethylene glycol, and the like, with propylene oxide. Next, the resulting propoxylated diol is reacted with ethylene oxide to produce the block copolymer. The second copolymer is prepared by polycondensing 2-amino-2-hydroxymethyl-1,3-propanediol, commonly known as TRIS, with... 

Amino-2-hydroxybenzoic acid, 2 668-669 physical properties of, 2 666t 2-Amino-2-(hydroxymethyl)-1,3-propanediol... 

Figure 7.9. A possible metrological traceability chain for the result of a measurement of protein in a sample of grain. aTris = 2-amino-2-hydroxymethyl-1,3-propanediol b Dumas apparatus is calibrated using tris CRM and grain samples are certified in an interlaboratory study cthe master instruments measure grain samples to act as the grower s calibrator for field measurements.

Ally loxymethyl-2-hydroxymethyl 1,3-propanediol Trinitrate Monoallylpentaeryth rite) ether Tri nit rote or Pentaerythritol-monoallylether Trinitrate, pi2.0N02... 

Ami no-2-hydroxymethyl-1,3-propanediol Trinitrate. See Tris(hydroxymethyl)-amino-methane Trinitrate... 

Pentaerythritolmonoallylether Trinitrate. See 2-Allyloxymethy 1-2-hydroxymethyl- 1,3-propanediol Trinitrate A138-R 2,4-Pentanedione. See Acetylacetone A53-L Pentanol. See Amyl Alcohol A394-R Penthrinit A147 (table)... 

Ethy l-2(hydroxymethyl)-1,3-propanediol Trinitrate or 2,2-Di(hydroxymethyl)-butanol T rinitrate. 

Pentaerythritol Monochlorohydrin Trinitrate [2-Chloromethyl-2-hydroxymethyl-1,3-propanediol Trinitrate (Name preferred by CA)]. CSH8CIN3O9, mw 289.59,N 14.5%, OB to CO2 —24.9% a white cryst solid, mp 65—6° (Ref 3) prepd by the action of P pentachloride on Petrin, yield 22.5% (Ref 3). It has been patented as an ingredient for expls, proplnts, and ign devices (Ref 2). For the expl props of a mixt of this compd with PE dichloride dinitrate, see above under the latter name Refs 1) Beil 1, <2782) 2) Westfalische-An-... 

Dinitroanil ino-trimethylolmethane N-(2,4-Dim trap henylamine)-trimethylolmeth-ane N (2,4-Dinitrophenyl)-(tris-hydroxy-methyl-metbyD-amine 2-(2, 4 -Dinitroanilino)-2-hydroxymethyl-1,3-propanediol 2,4-Di-nitropbenyltrimethylolmethylamine or 2,4-Dinitrophenyltrihydroxymethylmethylamine,... 

Figure 35. Rate of polymerization as a function of free energy change (-AGet) for photoinitiated CQ-NPG systems. Polymerizing monomer mixture 2-ethyl-2-(hydroxymethyl)-1,3-propanediol triacrylate (TMPTA) and ethylated bisphenol-A dimethacrylate (bis-EMA) (1 1). Polymerization was initiated by an argon-ion laser beam. Data from Ref. [175].

Fia. 5A.—Formation and Disappearance of O-a-L-Arabinosyl-D-glucoses with 0-Galactosidase of E. coli, ML 309.(Donor o-nitrophenyl a-L-arabinopyranoside. Acceptor D-glucose. 0.06 M 2-amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride buffer, pH 7.6 40°. I, 0-a-L-Arabinosyl-(l — 3)-D-glucose II, 0-a-L-arab-inosyl-(l —>4)-D-glucose III, 0-a-L-arabinosyl-(l — 6)-D-glucose. The disaccharides were estimated with triphenyltetrazolium chloride. The ordinate shows the extinction at 546 m. )... 

Fio. 9.—Dependence on pH of Maximal Velocity (Vm i) of the Hydrolysis of a-Lactose by /3-Galactosidase at 20°. (Buffers 0.05 M 2-amino-2-(hydroxymethyl)-1,3-propanediol-acetic acid. is expressed in micromoles of a-lactose hydrolyzed per min. per mg. of enzyme. X----X, in the absence of alkali salts.)... 

Because of the results found with p-(chloromercuri)benzoate and because /3-galactosidase is believed to be a sulfhydryl enzyme, it seemed advisable to investigate the effects of other sulfhydryl reagents. Virtually no inhibition of /3-galactosidase was found in the presence of iodoacetam-ide (9 X 10 M) over a period of 7 hours. A -Phenylmaleimide, at concentrations as high as 8.7 X 10 M, produced less than 10 % inhibition over a 20-hour period. However, when the concentration of V-phenyl-maleimide was raised to 9.1 X 10 M, assay of the incubation mixture revealed that 50% inhibition of /3-galactosidase occurred within a 2-hour period when the experiment was performed in 2-amino-2-(hydroxymethyl)-1,3-propanediol— acetic acid buffer, pH 8.0. Virtually no activity was lost when the latter experiment was repeated in phosphate buffer (Na salts) at the same pH. 

Meyer, Ber 25,1703-4(1892) 2-Allylexymethyl-2-hydroxymethyl-1,3> propanediol Trinitrate Monoollylpentoeryth-ritol ether Trinitrate or Pentaerythritol-monoollylether Trinitrate, pHj.ONO,... 

---