2-Hydroxylethyl methacrylate

In consideration of the clinical importance of being able to visualize any implant material within the body, radio-opaque hydrogels for NPR have been formulated [69]. Copolymers of iodobenzoyl-oxo-ethyl methacrylate (4IEMA) and hydrophilic PVP or hydroxylethyl methacrylate (HEMA) exhibit appropriate swelling characteristics, viscoelastic mechanical properties, and excellent cytocompatibility [69]. Moreover, inclusion of the covalently attached iodine molecules allowed for hydrogel visualization via X-ray in a porcine cadaveric spine model [69],... 

Corresponding DLS and rheology studies to prove the validity of the Eq. (18) were performed on another thermoreversible system (three mixtures made of xanthan gum and locust bean gum (XG/LBG) (Richter et al. 2004b, 2005) and on the irreversibly radical chemical cross-linking system (W-vinylcaprolactam/ 2-hydroxylethyl- methacrylate/allylmethacrylate) (Richter et al. 2004c). 

The azide-modified poly(N-isopropylacrylamide-co-hydroxylethyl methacrylate) 34 was also used to cross-link with a hexaacetylene derivative of a-CD 35 to generate structurally similar porous hydrogels [50]. 

Scheme 10 Poly(Af-isopropylacrylamide-co-hydroxylethyl methacrylate)-based CuAAC cross-linked chemical hydrogels 36...

Figure 3.8 Synthesis of the glycomonomers and their polymerisation using the biotinylated initiator. HEMA 2-hydroxylethyl methacrylate. Reproduced with permission from V. Vazquez-Dorbatt and H.D. Maynard, Biomacromolecules, 2006,1, 2297. 2006, American Chemical Society [38]...

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