4- Hydroxybutanoic acid lactone

SYNS Y-(3480 Y-BL BLO BLON BUTYRIC ACID LACTONE a-BUTYROLACTONE Y-BUTYROLACTONE (FCC) BUTYRYL LACTONE 4-DEOXYTETRONIC ACID DIHYDRO-2(3H)-FURAN-ONE FEMA No. 3291 4-HYDROXYBUTANOIC ACID LACTONE Y-HYDROXYBUTYRIC ACID CYCLIC ESTER 4-HYDROXYBUTYRIC ACID Y-LACTONE Y-... 

G.l) (G.l) 2(3//)-Furanone dihydro-, butano-4-lactone, tetrahydrofuran-2-one, 4-butanolide, 4-hydroxybutanoic acid lactone, y-butyrolactone 196-48-0] FEMA 3291... 

Hydroxybutane. See 2-Butanol Hydroxybutanedioic acid. See N-Hydroxysuccinic acid 4-Hydroxybutanoic acid lactone. See Butyrolactone... 

GBL 4-Hydroxybutanoic acid lactone y-Hydroxybutyric acid cyclic ester 4-Hydroxybutyric acid y-lactone y-Hydroxybutyric acid lactone y-Hydroxybutyrolactone Tetrahydro-2-furanone... 

The formula and the carbonyl stretching frequency of the compound indicate that the compound is an ester. The formula also indicates that the compound is a cyclic ester, 4-hydroxybutanoic acid lactone. The resonance at 178.1 ppm corresponds to the carbonyl carbon the resonance at... 

A soln. of 3-hydroxymethyl-4-(3,4-methylenedioxyphenyl)-4-hydroxybutanoic acid lactone in benzene chromatographed over Woelm neutral alumina (activity III), and eluted with benzene-chloroform (1 2) 3-(a-hydroxy-3,4-methylene-... 

The use of bromodeoxy lactones as chiral building blocks for the stereoselective preparation of natural compounds was also explored. Thus, both (5)-and (J )-carnitine, (S)- and (J )-4-amino-3-hydroxybutanoic acid (GABOB), compounds of high relevance for the central nervous system, as well as musc-aridine and 6-deoxyascorbic acid, were prepared by simple transformations of the bromodeoxy aldonolactones. 

Synonyms DL-3-Butyrolactone DL-P-Butyrolactone ( )-p-Butyrolactone DL-3-Hydroxybutanoic acid p-lactone DL-Hydroxybutyric acid lactone DL-3-Hydroxybutyric acid lactone DL-Hydroxybutyric acid p-lactone DL-4-Methyl-2-oxetanone ( )-4-Methyl-2-oxetanone DL-P-Methylpropiolactone... 

When 4-hydroxybutanoic acid is treated with an acid catalyst, it forms a lactone (a cyclic ester). Draw the structural formula of this lactone and propose a mechanism for its formation. 

Nomenclature of lactones is based on the nomenclature of hydroxycarboxyhc acids. The simplest P-lactone hypothetically derived from p-hydroxycarboxyhc acids is propano-3-lactone (formerly also known as 3-propanohde and P-propiolactone, 8-95), which can be considered an internal ester of 3-hydroxypropanoic acid. The simplest y-lactone is butano-4-lactone, also known as 4-butanolide or y-butyrolactone (8-96), which is derived from 4-hydroxybutanoic acid. The basic member of the homologous series of 5-lactones is pentano-5-lactone, also known as 5-pentanohde or 5-valerolactone (8-97), which is derived from... 

The lactone of 4-hydroxybutanoic acid is stable in aqueous acid solution. However, when it is dissolved in aqueous acid labeled with 0, the lactone incorporates 0. Which oxygen atom of the lactone is labeled ... 

Mote recently, treatment of 3-hydroxybutanoic acid (9) under the Yamaguchi lactonization conditions of high dilution gave, in... 

These terpene notes are supported by (Z)-3-hexenol, (E)-2-hexenal, (E)-2-hexenol with their fresh, green character. Gamma- and delta-lactones (4-decanolide, 5-decan-olide, 4-dodecanolide, 5-dodecanolide-(Z)-7-decen-5-olide) impart the sweet, creamy, buttery, peach and apricot character. 2,5-Dimethyl-4-hydroxy-furan-3(2H)-one and 2,5-dimethyl-4-methoxy-furan-3(2H)-one are responsible for the sweet creamy fruity body. A bouquet of esters imparts the overall fruity character (mainly esters of ethyl-, (Z)-3-hexenyl and butyl alcohol with acetic-, butanoic-, 2-butenoic, 3-hydroxybutanoic- and hexanoic acid). 

Esters constituted the largest family and included acetates (ethyl, propyl, isobutyl, butyl, isoamyl, and phenethyl), ethyl esters of fatty acids (propanoate, isobutanoate, butanoate, hexanoate, octanoate, 3-hydroxybutanoate, 3-hydroxyhexanoate and furcate), ethyl esters of organic acids (pyruvate, lactate, ethyl myristate, diethyl malate and, mono- and diethyl succinate) and various other esters, such as methyl butanoate, isobutyl lactate and phenylethyl octanoate. The acids quantified included isobutanoic, butanoic, hexanoic, octanoic, decanoic, lauiic and 3-methylbutanoic. The lactones included y-butyrolactone, pantolactone, y-decalactone and E- and Z-oak lactone and the terpenes included neral d-terpineol, P-dtronellol and Z-nerolidol. The aldehyde family comprised acetaldehyde, benzaldehyde, furfural, 5-methylfurfural and octanal, and the phenol family included eugenol, 4-ethylphenol and 4-ethylguaiacol. Finally, 1,1-diethoxyethane, acetoin, sotolon, 2, 3-butanedione, p-cymene and methionol were also determined. 

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