2 -Hydroxybiphenyl-2-sulfonate

A variation of the pathway in which 2 -hydroxybiphenyl-2-sulfinate is converted to 2 -hydroxybiphenyl-2-sulfonate (HBPSo) has been reported [26,62], In this alternate desulfurization pathway, the HBPSo further spontaneously cyclizes to sultone , BPSo. The latter is a substrate for DszA (Fig. 2), and is desulfurized to 2, 2 -dihydroxybiphenyl (DHBP) and sulfite. 

Wick LY, PM Gschwend (1998) Source and chemodynamic behaviour of diphenyl sulfone and ortho- and /lara-hydroxybiphenyl in a small lake receiving discharges from an adjacent superfund site. Environ Sci Technol 32 1319-1328. 

IGTS8 or simply IGTS8. The metabolic pathway in Rhodococcus sp. IGTS8 was delineated in the early 1990s [62], The pathway consists of four enzymes. DBT is converted to 2-hydroxybiphenyl (HBP) and sulfite via a 4-step pathway and the following intermediates DBT sulfoxide (dibenzothiophene-5-oxide, DBTO), DBT sulfone (dibenzothiophene-5,5-dioxide, DBT02) and hydroxyphenyl benzene sulfonate (phenol-phenyl sulfinate, HBPSi). 

Most recently, a new bifunctional phosphine catalyst, (2 -hydroxybiphenyl-2-yl)-diphenylphosphane 225, has been developed for the selective aza-MBH reaction and aza-MBH domino reaction of iV-sulfonated imines with acrolein under mild conditions in moderate to excellent yields (Scheme 2.111). The possible catalytic cycle of the domino reaction and aza-MBH reaction has been proposed. The aza-MBH/Michael/aldol/dehydrate domino reaction also provides an efficient method to synthesize tetrahydropyridine... 

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