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Hydroxyamic acids

An appraisal has been made of the available kinetic data on the acid hydrolyses of hydroxyamic acids. For A-substituted hydroxamic acids both A-2 and A-1 paths are recognized, but for primary hydroxamic acids there is evidence only for the A-2... [Pg.57]

Inhibition of HDACs is one key mechanism to reactivate the expression of these misregulated genes. The astounding tumor specificity of many HDAC inhibitors relays the potential for many of these new compounds for the treatment of cancer and perhaps other disorders. There are five classes of HDAC inhibitors (reviewed in Refs. 51 and 52) including (i) short-chain fatty adds such as sodium- -butyrate (ii) hydroxyamic acids, such as trichostatin A (TSA), suberoylanilide hydroxamic add (SAHA), m-carboxycinnamic acid bishydroxamic acid (CBHA), azelaic bishydroxamic acid (ABHA), and... [Pg.472]

Hydroxyamic acids Suberoylanilide hydroxamic acid (SAHA) Apoptosis, differentiation, and cell cycle arrest... [Pg.474]

Hydroxyamic acids Oxamflatin Apoptosis and cell cycle arrest... [Pg.474]

Hydroxyamic acids/ cyclic tetrapeptide Cyclic hydroxamic acid-containing peptide (CHAP) Cell cycle arrest... [Pg.474]

This test is based on the following reactions where R and R are di- or poly functional. The hydroxyamic acid from the polyester reacts with the ferric ion to form an inner complex salt which is water-soluble and violet or purple in colour for most hydroxamic acids. [Pg.335]

Without additional reagents Isocyanates from hydroxyamic acids via aeetoacetyl hydroxamates... [Pg.126]

See other pages where Hydroxyamic acids is mentioned: [Pg.892]    [Pg.225]    [Pg.892]    [Pg.340]    [Pg.16]    [Pg.343]    [Pg.674]    [Pg.21]    [Pg.81]    [Pg.653]    [Pg.892]    [Pg.225]    [Pg.892]    [Pg.340]    [Pg.16]    [Pg.343]    [Pg.674]    [Pg.21]    [Pg.81]    [Pg.653]   
See also in sourсe #XX -- [ Pg.320 ]



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