2.3.6- Trimethyl-5- 3 -hydroxy

Durch Reduktion von 1-Hydroxy-2,4,5-trimethyl-imidazol-3-oxid mit Natriumhydrogensulfit wird 2,4.5-Trimethyl-imidazol in 20% Ausbeute erhalten510. 

Etheno bridge inserted between positions 6 and 14 rings, plus hydroxy, trimethyl propyl substitution on position 7. 

Hydroxy-trimethyl- E9b/2, 268f. (Butandion + H2N-CHR-CO-NH2) Pyrazin-l-oxid 2(or 3)-Propyl-E9b/2, 306 (N-Oxidat.) Pyrimidine... 

The reaction products of TYZOR TPT with 2—4 moles of 1,3-diols having two to three alkyl substituents, such as 2,2,4-trimethyl-l,3-pentanediol, gives complexes that could be used as cross-linking agents for hydroxy group containing powdered lacquer resins (76). 

Fig. 4. Starting materials and iatermediates ia the TMHQ syatheses 2,3,6-trimethylpheaol [2416-94-6] (16), 2,3,5-trimethylquiaoae [935-92-2] (17), 2,4,6-trimethylpheaol [527-60-6] (18), and 4-hydroxy-2,4,6-trimethyl-2,5-cyclohexadien-l-one [2875052-9] (19).

Chroman-6-carboxylic acid, 8-hydroxy-2-methyl-4-0X0—see Rosellinic acid, 718 Chroman-2,7-dicarboxylic acid, 2,4,4-trimethyl-formation, 3, 733... 

Imidazole, 4-formyl-5-hydroxy-l-phenyl-mesoionic, 5, 372 Imidazole, 2-formyl-1-methyl-mass spectra, S, 360 Imidazole, 2-formyl-l,4,5-trimethyl-... 

Imidazolinium perchlorate, 4-hydroxy-2,5,5-trimethyl-4-phenyl-synthesis, S, 487 Imidazolinium salts antistatic agents, 1, 409 Imidazolinium salts, 1-vinyl-polymerization, 1, 280 Imidazolin-2-one, 1-cyano-synthesis, S, 482 Imidazolin-2-one, 4,5-dialkyl-synthesis, S, 491 Imidazolin-2-one, 4,5-diaryl-bromination, S, 399-400 lmidazolin-2-one, 4,5-di( p-bromophenyl)-reactions... 

Lumazine, 7-hydroxy-l,3-dimethyl-methylation, 3, 297 oxidation, 3, 307 reactions, 3, 296 sulfurization, 3, 297 Lumazine, 7-hydroxy-1,3,6-trimethyl-5-oxide... 

Boekelheide rearrangement, 3, 303 Lumazine, 6,7,8-trimethyl-hydrogen exchange, 3, 303 Lumazine, 1,3,6-trimethyl-7-hydroxy-bromination, 3, 302 Lumazinecarboxylic acid occurence, 3, 324 Lumazine-6-carboxylic acid methylation, 3, 297... 

Pyrrolo[3,2-c]pyridine, 4-hydroxy-tautomerism, 4, 500 Pyrrolo[3,2-c]pyridine, 2,3,3-trimethyl-methylation, 4, 513 Pyrrolo[3,4-6]pyridine, 2-methyl-UV spectra, 4, 501 Pyrrolo[3,4-c]pyridine, 2-methyl-UV spectra, 4, 501 Pyrrolopyridines acylation, 4, 504 bromination, 4, 505 diazo coupling, 4, 506 NMR, 4, 498... 

Janus Red B 3-[(2-hydroxy-l-naphtholenyl)azo-2-methylphenylazo]A, Af,Af-trimethyl-benzenaminium chloride [2636-31-9] M 460.0. Crystd from Et0H/H20 (1 1 v/v) and dry in vacuum. Store in a dark bottle. 

Trihydroxypteridine exists predominantly in the dioxo-mono-hydroxy form 191(R = H), its ultraviolet spectrum closely resembling those of both the 1- and the 3-methyl derivatives and that of l,3-dimethyl-7-methoxypteridine-2,4-dione (191, R = Me). These spectra are quite different from those of 8-methyl- (192, R = H) and l,3,8-trimethyl-pteridine-2,4,7-trione (192, R = Me), which are similar to each other and to those of other 8-substituted pteridine-2,4,7-triones. However, the ultraviolet spectrum of 2,4,7-trihydroxypteri-dine does, indeed, show that a small proportion of the trioxo form is present at equilibrium. A somewhat larger proportion of the 6-methyl derivative exists in the trioxo form, although structure 193 predominates. The trioxo form (194) of 2,4,7 trihydroxy-l,3,6-trimethyl-pteridine is the most important tautomer, but the corresponding 6-carboxylic acid exists entirely in the monohydroxy-dioxo form 195. 

In systems such as the 2- and 6-hydroxypteridine series, rapid potentiometric or spectrophotometric pA determinations on neutral solutions usually give values near to the acidic pA of the hydrated series. (Exceptions include 2-hydroxy-4,6,7-trimethyl-, 6-hydroxy-7-methyl-, and 4,6-dihydroxy-pteridine, where the neutral solution contains comparable amounts of hydrated and anhydrous species. In such cases, rapid potentiometric titrations show two well-defined and separated curves, one for the hydrated, the other for the anhydrous, species.) Similarly, from solutions of the anion, an approximate pA value for the anhydrous species is obtained. For convenience, the anhydrous molecule is referred to as HX, its anion as X , the hydrated neutral molecule as HY, and its anion as Y, and the two equilibrium constants are defined as follows ... 

Chemical Name 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt... 

Chemical Name 2-hydroxy-N,N,N-trimethyl-ethanaminium salt with 2-hydroxy ben2oic acid... 

D,L-3-Hydroxy-N-methyl-morphinan Phenyl trimethyl ammonium chloride D-Tartaric acid... 

The methylation of 51.4 parts by weight of D,L-3-hydroxy-N-methyl-morphinan is carried out with a methylating solution obtained from 51.5 parts by weight of phenyl-trimethyl-ammonium-chloride. The D,L-3-methoxy-N-methyl-morphinan is isolated in the form of its hydrobromide, which melts with 1 mol of water at 92°-94°C, without water at 239°-240°C. The base isolated from the aqueous solution by means of sodium carbonate melts at 81°-83 C. 

Chemical Name 5-Hydroxy-a,Q, 4-trimethyl-3Common Name Pinol hydrate... 

The residue is dissolved in ether and the solution is washed with sodium chloride solution and then with a little sodium thiosulfate solution. The ethereal solution is dried over sodium sulfate and ether removed by distillation. A yield of 108 parts of 3,5,5-trimethyl-oxazolidine-2,4-dione is obtained having a melting point of 45° to 46°C with slight softening at 43°C. This represents a 75% theory yield on the ethyl o-hydroxy-iso-butyrate taken. The product may be further purified by dissolving the minimum quantity of dry ether and cooling to -10°C. The product so obtained melts sharply at 45.5° to 46.5°C, according to U.S. Patent 2,559,011. 

R,2(tS),4aS,7R,8aR]-hexahydro-2-(l-hydroxy-i-methyl-2-pheny lethy[)-4,4,7-trimethyl-4H-t, 3-ben-zoxathiin4 yield 97% 100% de. 

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