9-Hydroxy-2-methyl-8-nitro-477-pyrido

Heating 9-hydroxy-2-methyl-8-nitro-4//-pyrido[ 1,2-a]pyrimidin-4-one 326 in dimethylformamide in the presence of hydrazine hydrate and Raney nickel at 50°C afforded 8-amino derivative 327 (92KGS1660). 8-Amino derivative 327 was also prepared from 8-phenylazo derivative 328. 

Hydroxy-2-methyl-4//-pyrido[ 1,2-a]pyrimidin-4-one 365 gave 8-sub-stituted derivatives in a reaction with different electrophilic reagents (Scheme 28) (92KGS1660). Nitration gave 8-nitro-9-hydroxy-2-methyl-pyridopyrimidin-4-one 326. Reaction with iodine afforded 8-iodo-... 

Diorganotin(IV) complexes 109, and complexes of 2-methyl- and 2-methyl-8-nitro-9-hydroxy-4/7-pyrido[l,2-a]pyrimidin-4-ones with Ag(I), Cu(II), Ni(II), Co(II), and Mn(II) ions (00MI23), 2,4-dimethyl-9-hydro-xypyrido[l,2-a]pyrimidinium perchlorate and its complexes with prasedynium, neodymium, samarium and europium (00MI24) were characterized... 

Diorganotin(IV) complexes (109) were prepared from 4 -pyrido[l,2- z]pyrimidin-4-ones with Me2SnCl2 and Ph2SnCl2 in dry CHCI3 (96MI4). Different complexes of 2-methyl-9-hydroxy-4/f-pyrido[l,2- z]pyrimidin-4-one and its 8-nitro derivative were prepared with Cu(I)Cl, Cu(II)Cl2, Ni(II)Cl2, Co(II)Cl2, Mn(II)Cl2, and Ag(I)N03 in EtOH (00MI23). Complexes of 2,4-dimethyl-9-hydroxypyrido[l,2-a]pyrimidinium salt were obtained with Pr(III), Nd(III), Sm(III), and Eu(III) ions in acetone (00MI24). 

Amino-6-hydroxy-4-hydroxy-methyl-3-phenyl- E9a, 589 (7-OH — 4-Ar — < 1,2-oxazolo-[3,4-d]pyridazine)/Red.) Pyrido[l,2-a]benzimidazol 7-Nitro-... 

Pyridazine 4-Amino-5-nitro-3-phenyl- E9a, 617 (H -> NH2) Pyrido[2,3-d pyrimidin 6-Cyan-4-hydroxy-7-methoxy-2-methyl-E9c, 93 [2-NH2 —3-(CO—... 

Phthalazine l,4-Dihydroxy-5(or 6)-dimethylamino- E9a, 752 (subst. Phthalanhydrid/N2H4) lH-PyrazoI 5-Methyl-5-nitro-4-phenyl-4,5-dihydro- X/l, 426 Pyrido[2,3-d]pyrimidin 4-Hydroxy-2-oxo-l-propyl-1,2-dihydro- E9c,... 

Pyrido[2,3-c)pyridazin 3-Ethoxycar-bonyl-4-hydroxy-7-methyl-6-nitro- E9c, 3 (2-C1 — Py —... 

Pyridin 2-Aminocarbonyl-5-(3-nitro-benzoyl)- E13/2, 1319 (Aminocarbonylierung) Pyrido[3,2-f -l, 5-benzoxazepin 5-Hydroxy-9-methyl-3-nitro- E9d,... 

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