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Hydrolytic degradation modifications

In dentistry, silicones are primarily used as dental-impression materials where chemical- and bioinertness are critical, and, thus, thoroughly evaluated.546 The development of a method for the detection of antibodies to silicones has been reviewed,547 as the search for novel silicone biomaterials continues. Thus, aromatic polyamide-silicone resins have been reviewed as a new class of biomaterials.548 In a short review, the comparison of silicones with their major competitor in biomaterials, polyurethanes, has been conducted.549 But silicones are also used in the modification of polyurethanes and other polymers via co-polymerization, formation of IPNs, blending, or functionalization by grafting, affecting both bulk and surface characteristics of the materials, as discussed in the recent reviews.550-552 A number of papers deal specifically with surface modification of silicones for medical applications, as described in a recent reference.555 The role of silicones in biodegradable polyurethane co-polymers,554 and in other hydrolytically degradable co-polymers,555 was recently studied. [Pg.681]

Macrolide, Lincosamide, and TVpe B Streptogramin Resistance Due to Inactivation, Hydrolytic Degradation, or Modification by a Certain Transferase of the Drugs in Clinically Isolated Bacteria... [Pg.475]

Water absorption of LCPs is extremely low. Hydrolysis resistance in LCP is good and can be increased by modification, e.g., with graphite. Extended exposure at high temperatures results in gradual hydrolytic degradation. [Pg.792]

Proteins are subject to a variety of chemical modification/degradation reactions, viz. deamidation, isomerization, hydrolysis, disulfide scrambling, beta-elimination, and oxidation. The principal hydrolytic mechanisms of degradation include peptide bond... [Pg.293]


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Hydrolytic

Hydrolytic degradation

Hydrolytic modifications

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