Hydrolysis of Collagen

Gelatin is a protein, made from the hydrolysis of collagen, a protein that makes up about a third of all mammalian tissue. Collagen is a key component of connective tissues, tendons, and bones. 

Collagenase specifically catalyzes the hydrolysis of collagen, and is used in debridement of dermal ulcers and bums (191). It, like chymopapain, is also useful in the treatment of herniated lumbar disks (192,193). The rationale for collagenase treatment in this instance is based on the preponderance of collagen in herniated disk tissue, and the inability of other enzymes to dissolve collagen (194). 

Gelatin is the product obtained from the acid, alkaline, or enzymatic hydrolysis of collagen, the chief protein component... 

The typical biopolymers used for the preparation of micro- and nanogels are polysaccharides (Scheme 11) cellulose (CL), chitosan (CS), hyaluronan (HA), heparin, pullulan (PuL), dextran, and gelatin - a proteinaceous polyamolytic gel obtained by partial hydrolysis of collagen. Gelatine microgels are addressed by Landfester and Musyanovych in another chapter of this issue [5] and will thus not be discussed further here. 

The other chiral component, the lactam 323, is clearly a cyclised version of 5-hydroxy-lysine 330. This and hydroxyproline 331 occur in the connective protein collagen. The hydroxy groups are added after the collagen is assembled but as they can be obtained by hydrolysis of collagen, they are members of the chiral pool. 

Gelatin is a heterogeneous product prepared by the hydrolysis of collagen, the principal constituent of connective tissue. The suitability of gelatin for capsule manufacture is due to the following properties ... 

Hydrolysis of collagen and muscle CSTR with UF membrane Meat tenderization... 

Gelatin is a protein product formed by the partial hydrolysis of collagen. It has a unique gel-forming ability and is used in the food industry as a stabilizer, texturizer, thickener, or foaming agent in ice cream, jam, yogurt. 

CAS 9000-70-8 EINECS/ELINCS 232-554-6 Synonyms Gelatine Gelatins White gelatin Definition Complex combination of proteins obtained from partial hydrolysis of collagen derived from animal skin, connective tissues, and bones Type A is derived from acid-treated precursor. Type B from alkali-treated precursor... 

Gelatines are produced by the partial hydrolysis of collagen. In Europe, gelatine is mainly produced from fresh bones, from which yields of up to 12% are obtained. For this, the bones are first demineralized to osseine with hydrochloric acid. Pigskin provides the main source of gelatine in the United States. 

Gelatin may be defined as a protein made soluble by hydrolysis of collagen derived from the skin, white connective tissue and bones of animals. It is distinguished from animal glue by the way it is isolated from the raw material. For this purpose more purification is needed than with the preparation of glue. In this way a product of high quality is obtained [422]. 

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