Hydrogen peroxide Aluminum chloride

HYDROXYLATION Hydrogen peroxide-Aluminum chloride. Potassium osmatc. 

The synthesis of 2,4-dihydroxyacetophenone [89-84-9] (21) by acylation reactions of resorcinol has been extensively studied. The reaction is performed using acetic anhydride (104), acetyl chloride (105), or acetic acid (106). The esterification of resorcinol by acetic anhydride followed by the isomerization of the diacetate intermediate has also been described in the presence of zinc chloride (107). Alkylation of resorcinol can be carried out using ethers (108), olefins (109), or alcohols (110). The catalysts which are generally used include sulfuric acid, phosphoric and polyphosphoric acids, acidic resins, or aluminum and iron derivatives. 2-Chlororesorcinol [6201-65-1] (22) is obtained by a sulfonation—chloration—desulfonation technique (111). 1,2,4-Trihydroxybenzene [533-73-3] (23) is obtained by hydroxylation of resorcinol using hydrogen peroxide (112) or peracids (113). 

Aluminum Ammonia, anhydrous Chlorinated hydrocarbons, halogens, steam Mercury, halogens, hypochlorites, chlorites, chlorine(I) oxide, hydrofluoric acid (anhydrous), hydrogen peroxide, chromium(VI) oxide, nitrogen dioxide, chromyl(VI) chloride, sulfinyl chloride, magnesium perchlorate, peroxodisul-fates, phosphorus pentoxide, acetaldehyde, ethylene oxide, acrolein, gold(III) chloride... 

The third method of levodopa synthesis consists of the acetylation of tyrosine using acetylchlo-ride in the presence of aluminum chloride and the subsequent oxidative deacylation of the formed 3-acetyltyrosine (10.1.2) using hydrogen peroxide in sodium hydroxide solution [4-7]. 

Phenanthrenequinone has been prepared by treatment of phe-nanthrene with chromic acid in acetic acid 5 potassium dichromate in sulfuric acid 3-6 hydrogen peroxide in acetic acid 6 7 and selenium dioxide above 250°.8 It can also be prepared from benzil with aluminum chloride at 120° 9 and from biphenyl-2,2 -dialdehyde with potassium cyanide.10... 

Methylenetriphenylphosphorane, 254 Titanium(IV) chloride-Lithium aluminum hydride, 310 (Z)-Alkenes By elimination reactions Dichlorobis(cyclopentadienyl)-titanium, 102 Hydrogen peroxide, 145 By hydrogenation of carbon-carbon triple bonds... 

Methyl phenyl sulfoxide has also been prepared from thio-anisole by the action of hydrogen peroxide,2,3 lead tetraacetate,4 and dinitrogen tetroxide,5,6 and from methanesulfinyl chloride and benzene with anhydrous aluminum chloride.7... 

Acetic anhydride Aluminum chloride Sodium hydroxide Hydrogen peroxide Sodium borohydride Hydrochloric acid... 

Methyl />-tolyl sulfone has been prepared by oxidation of methyl 7>-tolyl sulfide with hydrogen peroxide 4 r or ruthenium tetroxide,6 by alkylation of sodium -toluenesullinate with methyl iodide 7,8 or with methyl potassium sulfate,9 by decarboxylation of -tolylsulfonylacetic acid,7 by thermal decomposition of tetramethylammonium -toluenesulfinate,10 by reaction of cw-bis-(%tolylsulfonvl)-ethene with sodium hydroxide (low yield),11 by the reaction of methanesulfonyl chloride with toluene in the presence of aluminum chloride (mixture of isomers),12 by... 

Aromatic kydroxylation. Addition of hydrogen peroxide (0.05 mole of 90%, Du Pont) to a stirred solution or slurry of aluminum chloride (0.075-0.10 mole) in... 

Borane, which is used as a complex with tetrahydrofuran [992] or dimethyl sulfide [611, 992] or generated in situ from lithium borohydride with boron trifluoride etherate [646] or sodium borohydride with aluminum chloride [184], reacts with 3 mol of an alkene to form a tertiary borane. The oxidation with alkaline hydrogen peroxide [183, 992, 1201] or with trimethylamine oxide [991, 992] yields an alcohol (equations 598 and 599). 

Two syntheses of this alkaloid (119) have been reported. In one of them (120), starting from conessine (XCVI), the more reactive 3/3-nitrogen was protected by a selective reaction with 1 mole of hydrogen peroxide to form the 3-mono-IV-oxide CXX subsequent treatment with cyanogen bromide yielded iV-cyanoconessimine-3-IV -oxide (CXXI) which on reduction of the A -oxide grouping with sodium borohydride and aluminum chloride followed by alkaline hydrolysis yielded conessimine. 

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