Hydrogen fluoride-amine

Reactivity Hydrolysis products Hydrogen fluoride, amines and complex organo phosphates. 

Fluorination by cleavage of ethers has been investigated with a variety of hydrogen fluoride/ amine systems. Thus, the fluorinating reactivity is as follows ... 

Figure 2. Amount of hydrogen fluoride required to combine with different amines to form stable hydrogen fluoride/amine solutions at various temperatures A = pyridine O = triethylamine = melamine43...

Hydrogen Fluoride/Pyridine and Hydrogen Fluoride/Amines... 

Summarizing, it can be stated that hydrogen fluoride/pyridine and hydrogen fluoride/amine mixtures are useful for the synthesis of simple secondary and tertiary alkyl fluorides, but probably arc not suitable for fluorination reactions in complex multifunctional structures due to the highly acidic properties of these reagents. 

Another highly effective and convenient hydrogen fluoride/amine reagent for the hydrofluorination of alkenes is the solution of 14% melamine in 86% hydrogen fluoride (Table... 

Another highly effective and convenient hydrogen fluoride/amine reagent for the hydrofluorination of alkenes is the solution of 14% melamine in 86% hydrogen fluoride (w/w)46,47 (Table 3). The two-phase mixture of this reagent with pentane or carbon tetrachloride is a suitable system for repeated use47 (Table 4). 

Hydrogen fluoride-amine. 16, 286-287. I Oxidative fluorination. y,8-Difluoro anode when dienoic esters are subjected ti. A chemical process employing 3HF-Et-,N 3-halotetrahydropyrans and ally alcohol case study, only with NBS). 

Treatment of some epoxyaldonolactones with hydrogen fluoride-amine complexes has afforded products of epoxide opening with fluoride ion, e.g. 3-5." Epoxy derivatives 6 have been opened by fluoride ion [Ti(0 Pr)4 - Tip4] at the more hindered position to give deoxyfluoro compounds 7," and epoxide 8 has been regioselectively opened at C-3 to give the corresponding 3-deoxy-3-fluoro derivative. ... 

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