Hydrogen binding networks

Figure 12 2D structural representation of the SG Glu207Gln mutant in complex with 2 illustrating the hydrogen binding network for the glucose part and the mechanistic role of the catalytic glutamic acid residues (circled). 

Figure 12 Hydrogen bonding network involved in the binding of WINS4954 analogues to HRV-14.

Fig. 9 X-ray structure of bicyclic piperazinone inhibitor with thrombin (PDB ID 1G37). Piper-azinone inhibitor is shown as yellow sticks, and the receptor binding site is shown as transparent surface. The extensive hydrogen bonding network with receptor and water is shown as yellow dots...

G. A. Kicska, P. C. Tyler, G. B. Evans, R. H. Fumeaux, W. Shi, A. Fedorov, A. Lewandowicz, S. M. Cahill, S. C. Almo, and V. L. Schramm, Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase, Biochemistry, 41 (2002) 14489-14498. 

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