Hydrocodone bitartrate/chlorpheniramine maleate

Hydrocodone bitartrate/chlorpheniramine maleate is an anti-tussive combination. Hydrocodone suppresses cough reflex stimulates opiate receptors in the CNS and peripherally blocks pain impulse generation. Chlorpheniramine competitively antagonizes histamine at H,-receptor sites. They provide relief of cough and rhinorrhea and symptomatic relief of stubborn cough and runny nose caused by cold or allergy. 

Tussafed Syrup—dextromethorphan HBr, carbinoxam-ine maleate, pseudoephedrine HC1 Tussend Tablets—hydrocodone bitartrate, chlorpheniramine, pseudoephedrine HC1 Vanex HD Liquid—hydrocodone bitartrate, chloqihen-iramine, phenylephrine HC1... 

BITARTRATE/CHLORPHENIRAMINE MALEATE (S-T Forte 2 liquid 2.5 mg hydrocodone bitartrate and 2 mg chlorpheniramine maleate)... 

Each teaspoonful (5 mL) of TUSSIONEX Pennkinetic extended-release suspension contains hydrocodone polistirex equivalent to 10 mg of hydrocodone bitartrate and chlorpheniramine polistirex equivalent to 8 mg of chlorpheniramine maleate. TUSSIONEX Pennkinetic extended-release suspension provides up to 12-hour relief per dose. Hydrocodone is a centrally acting narcotic antitussive. Chlorpheniramine is an antihistamine. TUSSIONEX Pennkinetic extended-release suspension is for oral use only. Hydrocodone polistirex sulfonated styrene-divinylbenzene copolymer complex with... 

Hydrocodone bitartrate is absolutely contraindicated in patients with known hypersensitivity reactions to hydrocodone. Commercial preparations may also contain sulfite compounds that can produce allergic reactions, including bronchospasm and anaphylaxis, in certain susceptible individuals, particularly asthmatic patients. In addition, the dye tartrazine is present in one preparation of hydrocodone bitartrate, combined with chlorpheniramine maleate and phenylephrine hydrochloride, that is used as an antitussive and expectorant agent (Vanex). Also known as FD C yellow No. 5, tartrazine can cause asthmatic and other allergic reactions in some susceptible patients, especially those with aspirin sensitivities. 

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See also in sourсe #XX -- [ ]

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