Anti-tussives

Anti tussive Antitussives Antiulcer therapy Antivert Antiviral agents... 

Alkaloids range from the belladonna alkaloids, such as atropine and scopalomine—which are used as poisons, cold remedies, and truth serums —to dextromethorphan, a cough suppressant (anti-tussive). But the most widely known alkaloids are the opiates, such as morphine, heroin, fentanyl, oxycodone, and methadone. These act on... 

Mitragynine. Mitragynine (62) ethanedisulfonate exhibits analgesic and anti-tussive properties in animals (335). It has only weak respiratory depressant activity. 

There are also known cases of drug enantiomers that possess completely different therapeutic properties. The (+)-2/ ,35 -stereoisomer of propoxyphene (dextropropoxyphene) is marketed as an analgesic agent, whereas its enantiomer ( )-(25, 3/ )-propoxyphene (levopropoxyphene) is available as an effective anti-tussive agent [3]. The enantiomers of some chiral drugs are known to possess essentially identical qualitative and quantitative pharmacological activities, for example, the antihistamine promethazine, which is marketed as a racemate [5]. 

The salt of citric acid and 3-phenyl-5-diethylaminoethyl oxadiazole which possesses an anti-tussive activity, is known under the trade names "Oxolamine", "Perebron and "Bredon 22a). 

ANALGESICS,ANTIPYRETICS,AND ANTIINFLAMMATORY AGENTS] (Vol2) -as anti tussive [EXPECTORANTS, ANTITUSSIVES AND RELATED AGENTS] (Vol 9)... 

Paul DB and Dobberstein RH (1994) Expectorants, anti-tussives, and related agents. Kirk-Othmer Encyclopedia of Chemical Technology, 4th edn, Vol 9. Wiley, New York, pp 1061-1081. 

Drugs in Schedule V are generally reserved for anti-tussive and antidiarrheal purposes with the least potential for abuse of the scheduled substances. 

Many opiate analgesics are effective cough suppressants (also called anti-tussives), although only codeine and dihydrocodeine are generally used for this purpose. As there is a dissociation between the anti-tussive and analgesic action of the opiates, dextromethorphan and noscapine are now commonly used as cough suppressants because of their efficacy and lack of dependence-producing properties. 

---