Human Retaining P-Glucosidase Active Site Residues

Mapping of Human Retaining p-Glucosidase Active Site Residues 

Another intriguing feature of the epoxide and aziridine probes is the highly potent activity they display. Next to offering a suitable electrophile (epoxides, acy-laziridine) to the general acid/base, the (putative) half-chair coirformation they 

National Design of Activity-Based Retaining p-Exoglucosidase Probes 

Selection of (putative) acid/base, nucleophile residues 

In vitro labeling with activity-based probes (ABPs) 

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