Human population mutagenesis

A fundamental issue in genetic toxicology is that environmental chemicals may cause mutation in human germ cells and thereby pose a health risk for future generations. Because of this possibility, there is a major effort to detect chemicals that induce mutation in man. However, mutagenesis is not amenable to the collection of data on human populations, except for effects in somatic cells. 

Newcombe, H.B. Techniques for monitoring and assessing the significance of mutagenesis in human populations, pp. 57-77. In A. Hollaender, Ed. Chemical Mutagens Principles and Methods for Their Detection. Vol. 3. 

Techniques for Monitoring and Assessing the Significance of Mutagenesis in Human Populations... 

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