Human histone deacetylase family

Gao L, Cueto MA, Asselbergs F, Atadja P (2002) Cloning and functional characterization of HDACl Is, a novel member of the human histone deacetylase family. J Biol Chem 277(28) 25748-25755... [Pg.287]

Gray SG, Ekstrom TJ (2001) The human histone deacetylase family. Exp Cell Res 262(2) 75-83... [Pg.287]

Gray SG, Ekstrom TJ (2001) The human histone deacetylase family. Exp Cell Res 262 75—83 Greiner D, Bonaldi T, Eskeland R, Roemer E, Imhof A (2005) Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem BioH 143-145 Grozinger CM, Chao ED, Blackwell HE, Moazed D, Schreiber SL (2001) Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. J Biol Chem 276(42) 38837-38843... [Pg.423]

Fischle W, EmUiani S, Hendzel Ml, Nagase T, Nomura N, Voelter W, Verdin E (1999) A new family of human histone deacetylases related to Saccharomyces cerevisiae HDAlp. J Biol Chem 274(17) 11713-11720... [Pg.111]

One of the most-studied covalent modifications is the acetylation of the lysine residues of histone tails. The acetylation state of lysines of nucleosomal histones modulates chromatin structure and regulates gene transcriptional activity. The balance of lysine acetylation is controlled by the antagonistic action of two enzyme families histone deacetylases (HDACs) and histone acetyltransferases (HATs). In humans there are essentially three main HDAC subclasses [6]. [Pg.337]

Blander G, Guarente L (2004) The Sir2 family of protein deacetylases. Annu Rev of Biochem 73 417 35 Brinkmann H, Dahler AL, Popa C, Serewko MM, Parsons PG, Gabrielli BG, Burgess AJ, Saunders NA (2001) Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts. J Biol Chem 276 22491-22499... [Pg.421]

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