Human Genome Sciences

Venter JC et al The Sequence of the Human Genome. Science 2001 291 1304. (The issue [16 February] contains the Celera draft version and other articles dedicated to analyses of the human genome.)... 

Data from Venter JC et al The sequence of the human genome. Science 2001 291 1304. 

Venter JC, Adams MC, Sutton GG, Kerlavage AR, Smith HO, Hunkapil-ler M. Shotgun sequencing of the human genome. Science 1998 280 1540-1542. 

Wang DG, Fan JB, Siao CJ et al. Large-scale identification, mapping, and geno-typing of single-nucleotide polymorphisms in the human genome. Science 1998 280 1077-1082. 

Wang, D.G., et al., "Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome," Science 280, 1077-1082 (1998). 

Manning G, Whyte DB, Martinez T, et al. (2002) The protein kinase complement of the human genome. Science 298 1912-1934. 

Ethical research of the impfications of human genome science is an integral part of the German Human Genome Project. The results of the Human Genome... 

Mural, R.J., Adams, M.D., Myers, E.W., et ah A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science 296, 1661— 1671, 2002. 

An example is a chemokine called myeloid progenitor inhibitor factor-1 (MPIF-1), developed by Human Genome Sciences (HGS) for the treatment of patients with cancer to reduce the toxicity of chemotherapy. It was the hrst genomics-derived therapeutic product to enter clinical trials [37]. 

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