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Shotgun sequencing

Venter JC, Adams MC, Sutton GG, Kerlavage AR, Smith HO, Hunkapil-ler M. Shotgun sequencing of the human genome. Science 1998 280 1540-1542. [Pg.56]

Chapter 6 describes the computer methods developed by Dr. Roger Staden at the MRC Laboratory of Molecular Biology, Cambridge, for handling the sequence data produced by the rapid shotgun sequencing techniques described in Chapter 4. Since... [Pg.6]

In the shotgun sequencing procedure picking recombinant clones is a random procedure and it is often convenient, having sequenced from one end of a single-stranded insert, to turn the sequence around to be able to sequence from the other end. This is done using the clone tum-around procedure described by Winter... [Pg.128]

Environmental genome shotgun sequencing of the Sargasso Sea. Science 304 66—74... [Pg.129]

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Sequencing whole genome shotgun

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