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Human comparisons

Walle, U. K., Pesola, G. R., Walle, T., Stereoselective sulphate conjugation of salbutamol in humans comparison of hepatic, intestinal and platelet activity, Br. J. Clin. Pharmacol. 1993, 35, 413-418. [Pg.185]

A couple of additional experiments involving TMA-2 had been set up and started, but somehow never had enough fire to get completed. Studies on the optical isomers had gotten up to assays of 6 milligrams on each of the separate isomers, but had never been taken higher. The R isomer is much the more potent in rabbit assays, but the human comparisons remain unknown at present. Also, a study of the 14C labeled racemate (5 microcuries in 40 milligrams) was conducted with a view to metabolite analysis, but again, the project was abandoned before any results were obtained. In the rat, the 4-methoxyl carbon appeared as expired carbon dioxide to the extent of about 20%. And this is some four times the amount seen from either of the other two methoxyl carbon atoms. [Pg.442]

Culm-Merdek KE, von Moltke LL, Gan L, et al. Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans comparison with ritonavir. Clin Pharm Ther 2006 79 243-254. [Pg.662]

Mahmood I, Green MD, Fisher JE. Selection of the first-time dose in humans comparison of different approaches based on interspecies scahng of clearance. / Clin Pharmacol 2003 43(7) 692-7. [Pg.984]

Le Corre, P. Ratanasavanh, D. Chevanne, F. Gibassier, D. Sado, P. Le Verge, R. Guillouzo, A. In vitro assessment of stereoselective hepatic metabolism of disopyramide in humans comparison with in vivo data. Chirality 1991, 3, 405 11. [Pg.354]

Zou P, Zheng N, Yang Y, Yu LX, Sun D. 2012. Prediction of volume of distribution at steady state in humans comparison of different approaches. Expert Opin Drug Metab Toxicol 8 855-872. [Pg.81]

Riad LE, Chan KK, Sawchuk RJ. Determination of the relative formation and elimination clearance of 2 major carbamazepine metabolites in humans—comparison between traditional and pooled sample analysis. Pharm Res 1991 8(4) 541—543. [Pg.565]

Shimatani T, Inoue M, Kuroiwa T, Xu J, Nakamura M, Tazuma S, Ikawa K, Morikawa N. Lafutidine, a newly developed antiulcer drug, elevates postprandial intragastric pH and increases plasma calcitonin gene-related peptide and somatostatin concentrations in humans comparisons with famotidine. Dig Dis Sd 2006 51 114-20. [Pg.575]

New, R. R. C., Guard, P. W., Littlewood, G. M., Sandbank, B. M., and Flynn, M. J., 1994c, Administration of calcitonin to humans Comparison of intia-nasal and oral routes. Third European Symposium on Controlled Release Drug Delivery, Noordwijk aan Zee, The Netherlands, April 6-8. [Pg.284]

Benech, H., Batel, A., Rruvost, A., Thomas, J.-L., and Grognet, J.-M. (1998) Magnesium isotopic abundance measurement in humans comparison of two mass spectrometric methods. Magnes. Res., 11,91-102. [Pg.394]


See other pages where Human comparisons is mentioned: [Pg.94]    [Pg.9]    [Pg.388]    [Pg.97]    [Pg.33]    [Pg.46]    [Pg.539]    [Pg.218]    [Pg.122]   
See also in sourсe #XX -- [ Pg.122 ]




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