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HT-RNAi

HT-RNAi screens of mammalian cells primarily use either short interfering RNA (siRNA) or small-hairpin RNA (shRNA) libraries. Although there are similarities between the two platforms, screening using siRNA libraries has the advantages of having minimal... [Pg.89]

Fig. 1 The dual role of RNAi technology in drug development process. RNAi compounds are being extensively used as a drug target discovery and validation tool. At the same time, they hold the promise of being used as drugs themselves. HTS, high-throughput screening of small molecules ADMET, absorption, distribution, metabolism, excretion, toxicity studies. Fig. 1 The dual role of RNAi technology in drug development process. RNAi compounds are being extensively used as a drug target discovery and validation tool. At the same time, they hold the promise of being used as drugs themselves. HTS, high-throughput screening of small molecules ADMET, absorption, distribution, metabolism, excretion, toxicity studies.
See other pages where HT-RNAi is mentioned: [Pg.89]    [Pg.89]    [Pg.90]    [Pg.90]    [Pg.89]    [Pg.89]    [Pg.90]    [Pg.90]    [Pg.58]    [Pg.261]    [Pg.230]    [Pg.1117]    [Pg.800]    [Pg.320]   
See also in sourсe #XX -- [ Pg.89 , Pg.90 ]



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