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Hormone-sensitive Lipase HSL as a Drug Target in Diabetes

The assay is robust, easily handled, has a high signal-to-noise ratio and can be performed under high-throughput screening conditions using a robotic pipetting machine. We applied this assay in a 384-format to screen the Aventis compound collection for inhibitors of several lipases. One example, HSL is described below. [Pg.125]

Hormone-sensitive Lipase (HSL) as a Drug Target in Diabetes [Pg.125]


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As hormones

Diabetes drugs

Drug Sensitization

Drugs targeting

Hormonal drugs

Hormone targeting

Hormone-sensitive lipase

Targeted drugs

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