Homology regions

Figure 3. Comparison of the amino acid sequence of RHG of A. aculeatus with polygalacturonases PGI, PGII and PGC of A. niger. The most homologous region of the proteins is shown. Numbering is from the first amino acid of the signal peptide. Identical amino acids similar amino acids. The amino acid residues in bold type are referred to in the text.

Rel proteins contain a 280-amino acid homology region, which mediates both DNA binding and dimerization. DNA contact regions are located in the amino-terminal half and the residues responsible for the dimerization reside in the carboxy terminal half. 

Physical-Chemical Parameters for Human Core Domain PrP90-230 and Homologous Regions in Different Animals 1... 

HR1 Protein kinase C-related kinase homology region 1 homologs E(MF) 1(2) 1(1) ... 

Yu, H. et al. Identification of a cullin homology region in a subunit of the anaphase-promoting complex. Science 1998, 279, 1219-22. 

The UBA domain was initially identified as a short homology region of about 40 residues, which is found in a multitude of proteins involved in the ubiquitin system [46]. An alignment of some representative UBA domains is shown in Figure 12.2. For a more comprehensive overview, there are a number of excellent reviews... 

So far, six families of HAT have been described. The different groups have been made according to their sequence similarities between homolog regions and between their different HAT domains (reviewed in Torchia et al, 1998 Sterner and Berger 2000 see references therein). 

Figure 2. Gene-coding regions of xylose isomerases isolated from 5 bacterial strains. Homologous regions (x) are mapped from the computer-generated amino acid sequences minimum = 4aa e x sam = AT0S b x sam = ATCG sam x sam or b X e = ATCO...

Moran, M. F., Koch, C. A., Anderson, D., Ellis, C., England, L., Martin, G. S., and Pawson, T. (1990). Src homology region 2 domains direct protein-protein interactions in signal transduction, Proc Natl Acad Sci U S A 87,8622-6. 

Ludwig, S.R. et al., Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region. Proc. Natl Acad. Set USA, 86, 7092, 1989. 

Fig. 8.14 Domain structure of cytoplasmic tyrosine kinases. Linear representation of the domain structure of selected cytoplasmic tyrosine kinases. Details of the cytoplasmic tyrosine kinases Src 8.3.2 Jak, Tyk 11.1.5 Zap-70 11.2.2 Fak 11.3 JH Jak homology region. According to Taniguchi, (1995).

Fig. 11.5. Domain structure of the Jak kinases. JHl is the catalytic tyrosine kinase domain. JH2 shows similarity to a tyrosine kinase domain. The domains A—E are homologous elements of the Jak kinase family. JH Janus kinase homology region.

IR, MAP. The thin line represents crystallographically determined homologous regions of the five kinases (R. Karlsson and J.M. Sowadski, personal... 

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