Hollow microcapsules

Shchukin DG, Sukhorukov GB, Mohwald H (2003) Smart inorganic/organic nanocomposite hollow microcapsules. Angew Chem Int Ed Engl 42(37) 4472-4475... 

Hollow microcapsules have been obtained after dissolution of inorganic matrix at pH 1-2. During processing of firm insoluble cores by HCL, the osmotic pressure inside capsules tends to increase due to formation of soluble CaCl2 [8]. To avoid breaks of the microcapsule walls the process of dissolution was optimized by smoothly decreasing the pH value (incubating coated cores for 1 min successively at pH 4, 3, 2 and 1). 

The stable hollow microcapsules on the basis of natural polysaccharide alginic acid and protein protamine sulfate are formed via LbL method. The (PtS/AlA)4 microcapsules fabricated are promising for biomedical applications. 

Nanopartide Controllable Assembly, Fig. 8 Three diffm nt types of freestanding LBL nanostructures, (a) LBL structures in air al) microcantilever, (a2) miCTotu-bule, o3) hollow microcapsule, and ia4) thin planar film, (b) LBL structures at the air/liquid interface (W) LBL... 

Chaw, C.S., Yang, Y.Y., Lim, I.J., and Phan, T.T., Water-soluble betamethasone-loaded poly(lactide-co-glycolide) hollow microcapsules as a sustained release dosage form, J MicroencapsuL, 20 (3), 349-359, 2001. 

These hollow microcapsules have been extensively studied (permeability of the wall [4], mechanical properties [5,6], etc.) during the past few years, and different cores as well as different polyelectrolytes were used [7,8]. 

H. Kiesewetter, H. Moehwald, H. J. Meisehnan and H. Baumler, Biological cells as templates for hollow microcapsules. Journal of Microencapsulation, 18(3), 385-395 (2001). 

Q. Zhao, Changyou Gao, Jiacong Shen, Yu Li and Xiaobin Zhang, Incorporation of Carbon Nanotubes into Hollow Microcapsules Using a Removable Template Assembly,Macromolecular Rapid Communications, 25, 2014-2018 (2004). 

Floating hollow microcapsules Melatonin Gastroretentive drug delivery [66]... 

Feng, Z., Wang, Z., Gao, C., Shen, J. (2007). Template polymerization to fabricate hydrogen-bonded poly( acrylic acid)/poly(vinylpyrrolidone) hollow microcapsules with a pH-mediated swelling DesweUing property. Chemistry of Materials, 79(19), 4648 657. 

De Geest,B. G., Dejugnat, C, Prevot, M., Sukhorukov, G. B., Demeester, J., De Smedt, S. C. Setf-mpturing and hollow microcapsules prepared fiom bio-poly electrolyte coated microgels. Adv. Fund. Mater. 2007,17,531-537. 

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