Hochman mechanism

The metal dusting of pure metals, especially Fe, was studied extensively by Hochman2. The Hochman mechanism for the metal dusting of iron involves three steps. The first step is the formation of metastable iron carbide, FejC, on the surface of iron. This reaction requires carbon activities higher than unity. 

Reaction [6] generates iron powder or dust, thus explaining how bulk metal is converted to metallic powder. A schematic representation of the Hochman mechanism has been given by Grabke4. 

Wilde, B. E. and Kim, C. D., The R61e of Hydrogen in the Mechanism of Stress-corrosion Cracking of Austenitic Stainless Steel in Hot Chloride Media , Corrosion, 28, 350 (1972) Lin, F. and Hochman, R. F., Electrochemical Study of Stress-corrosion Cracking of Ti 8-1-1 Alloy and NaCl Solutions , Corrosion, 28, 182 (1972)... 

Hochman, J., Artursson, P., Mechanisms of absorption enhancement and tight junction regulation, J. Controlled Release 1994, 29, 253-267. 

Hochman JH, Fix JA, LeCluyse EL (1994) In vitro and in vivo analysis of the mechanism of absorption enhancement by palmitoylcarnitine. J Pharmacol Exp Ther 269 813-822 Hoffman A, Qadri B (2008) Eligen insulin-a system for the oral delivery of insulin for diabetes. IDrugs 11 433 41... 

Goldberg I, Nadler V, Hochman A. (1987). Mechanism of nitrogenase switch-off by oxygen. J. Bacteriol. 169, 874-879. 

E.N. Pugh, A Post Conference Evaluation of Our Understanding of the Failure Mechanisms, Stress Corrosion Cracking and Hydrogen Embrittlement of Iron Base Alloys NACE 5, R.W. Staehle, J.H. Hochman, R.D. McCright, and J.E. Slater, Ed., National Association of Corrosion Engineers, 1977, p 1977... 

The third mechanism is ionic interaction, which involves activity-dependent shifts in the intracellular and extracellular concentration of ions. Intense electrical activity during seizures is associated with transmembrane ionic currents, causing K and Cl" redistribution. Increasing K concentration in the extracellular milieu increases membrane excitability and has a slow synchronizing effect on neuronal networks (Jensen and Yaari, 1997). Extracellular chloride may also play a critical role in neuronal synchronization (Hochman et al., 1999). 

Hochman Y, Zakim D, Vessey DA. A kinetic mechanism for modulation ttf the activity rtf microsomal UOP glucuronyltransferase by i iospholipids Effects of lyscq osphatidyb cholines. J Biol Chem 1981 256 4783-4788. 

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