Hinge variations

Plate (single blade) A hinged flap that, by virtue of its position relative to airflow, creates a flow variation. This simplest form of damper, only used on small duct sizes, does not provide accurate control. 

The application of the genetotrophic principle by medical science is a long-range proposal. Many difficulties and intensive investigations in addition to natural conservatism, lie in its way, and it may be decades before it bears the best fruit. The possibilities arising out of its application hinge upon the prevalence and wideness of the variations in the body chemistry of human individuals. 

However, the studies on the hinge and Tyrl43 provided no information on the electron transfer from flavin-semiqumone to b 2-heme, the step which rate limits the catalytic cycle. In some elegant experiments, Tegoni et al. (1998) showed that the variation of the rate constant (In et) for this step correlates well with variations in the driving force (AG). Thus, this slow intra-molecular electron transfer is almost certainly controlled by thermodynamics. Tegoni et al. (1998) also provided some evidence that the faster, flavohydroquinone - b 2-heme, electron transfer may also be under thermodynamic control although this remains to be conclusively demonstrated. 

All rotary extractors employ deep beds of solids to be extracted, sometimes as much as two or more meters deep. Hence, rotary extractors are also termed deep-bed extractors. There are several mechanical variations of these extractors. Two variations have already been mentioned. Another variation is where the individual cells have hinged bottoms that swing open whenever the cell is to be emptied. In this variation, the solids slide against a common one-piece bottom that has an opening to allow solids to fall through when extraction is completed. Termed sliding plate. 

Conformational variation of L1L occurs at dynamical hinge points... 

The effector sites that interact with cells (e.g., IgE with mast cells) and with complement are on the constant (Fc) region of the heavy chains. Variations in the Fc region result in the classes and subclasses into which immunoglobulins are grouped IgM, IgG (four subclasses), IgA (two subclasses), IgD, and IgE. Their respective heavy chains are called p, y, a, 6, and e. The hinge region between the Fc and Fab portions, which is susceptible to proteolytic cleavage, controls the interaction between the Fab and Fc parts. The... 

Since the identities of the gonadotropic hormones remain uncertain, it is important before discussing assay procedures, to examine in some detail the various techniques for their preparation. Such methods may of themselves lead to differences in the composition or structure of the final products of extraction as well as to variations in the type of protein contaminants remaining in the purified hormone preparation. Since immunological procedures hinge on the availability of pure FSH and LH, it is likely that the results of such assays will vary depending on the methods by which these purified hormones have been obtained. 

Figure 37. Dihedral-angle variations for hinge mode (a) versus residue number (b) versus residue number (c) sidechain angles x1 versus residue number. Each bar corresponds to the change in the dihedral angle in going from the 1- A rms displaced closed structure to the 1-A rms displaced open structure.

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