Hill factor

In the Emax model above, plasma concentration and EC50 are raised to the power of n (Hill factor) equal to 1. A more general form of the equation is the sigmoid curve ... 

When E(C) is the observed effect at concentration C, Emax is the maximal effect (based on EEG components), K is the concentration at half-maximal effect, and N is the Hill factor, a constant expressing the sigmoidicity of the concentration-effect relationship. Subscripts A refer to the specific ligand of a ligand-gated ionotropic receptor. 

Linoleic acid A9 hydratase, which is involved in the linoleic acid saturation metabolism of Lactobacillus plantarum AKU 1009a, was cloned as his-tagged recombinant enz une, purified with affinity column, and characterized [30]. The enzyme required FAD as a cofactor for its activity, and the activity was enhanced by NADH. The maximum activities for hydration of linoleic acid and for dehydration of lO-hydroxy-czs-12-octadecenoic acid (HYA) were observed at 37°C, pH5.5, with 0.5M NaCl. C16 and CIS free fatty acids with cis-9 double bond served as substrates for hydration with CIO regiospecificity and (S) stereospecificity (Figure 22.9). 10-Hydroxy fatty acids served as substrates for dehydration reactions. The apparent value for linoleic acid was estimated to be 92 irM with its values at 2.6 x 10 s and Hill factor was 3.3. The apparent K value for HYA was estimated to be 98 iM with its values at 1.2 x 10 s ... 

For a short pipe of circular cross section, the conductance as calculated for an orifice from Eq. (6-82) is multiplied by a correction factor iC which may be approximated as (Kennard, Kinetic Theory of Gases, McGraw-Hill, New York, 1938, pp. 306-308)... 

FIG. 6-46 Friction factor for beds of solids. (From Leva, Fluidization, McGraw-Hill, New Yotk, 1959, p. 49. )... 

FIG. 14-34 Friction factor for frotF crossflow, sieve plates. To convert incFes to millimeters, multiply by 25.4. (Smith, Design of Equilibrium Stage Processes, McGraw-Hill, New Yoih, 1963. )... 

Woodson, W. E., Tillman, B. and Tillman, P. 1992 Human Factors Design Handbook. NY McGraw-Hill. 

Hounslow etal. (1988), Hounslow (1990a), Hostomsky and Jones (1991), Lister etal. (1995), Hill and Ng (1995) and Kumar and Ramkrishna (1996a,b) present numerical discretization schemes for solution of the population balance and compute correction factors in order to preserve total mass and number whilst Wojcik and Jones (1998a) evaluated various methods. 

Figure 2-15. Heat capacity correction factor. (From Chemical Engineer s Handbook, 5th Edition, R. Perry and C. Chilton, McGraw-Hill Co., 1973.)...

McCormick, E. J., Sanders, M. S. (1982). Human Factors in Engineering and Design (5th ed.). New York McGraw-Hill. 

Figure 5-28. Mixing scale-up factors referenced to experienced ratios of power per unit volume. By permission, Penny, W. R., Chem. Engr., Mar. 22,1971, McGraw-Hill, Inc., p. 88 [31].

Figure 10-47. Flow inside tubes for gas and vapors. Physical property factor depends on viscosity, specific heat, and thermal conductivity. (Used by permission Ning Hsing Chen, Chemical Engineering, V. 66, No. 1, 1959. McGraw-Hill, Inc. All rights reserved.)...

Figure 10-137. Heating and cooling in tube bundles—tube-side friction factor. (Used by permission Kern, D. Q. Process Heat Transfer, 1 Ed., p. 836, 1950. McGraw-Hill, Inc. All rights reserved. Using nomenclature of Standards of Tubular Exchanger Manufacturers Association.)...

In this model, the factor s introduces the asymmetry. Alternatively, a modified Hill equation can be used [1] ... 

Chilton, C. H., Six Tenths Factor, Applies to Complete Plant Costs. Chem. Eng, reprinted in Cost Engineering in the Process Industries Estimation, McGraw-Hill Book Co., 1960. 

Howell, J. R. A Catalog of Radiation Configuration Factors (McGraw-Hill, New York, 1982)... 

Jenny, H. (1941). "Factors of Soil Formation A System of Quantitative Pedology." McGraw-Hill, New York. 

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