High-throughput screening library design

Computational approaches towards the rational design of drug-like compound libraries. Comb. Chem. High-Throughput Screen. 2001, 4, 453 75. 

Matter, H., Baringhaus, K. H., Naumann, T., Kiabunde, T., Pirard, B., Computational approaches towards the rational design of drug-like compound libraries, Comb. Chem. High Throughput Screen. 2001, 4, 453-475. 

This novel class of PDF inhibitors was discovered through the high-throughput screening (HTS) and the virtual ligand screening (VLS) of over 10000 members of a library composed of molecules selected from DuPont s corporate collection, and designed to represent the broad diversity of bio-... 

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