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High-throughput Measurement of log D and pKa

ADME Absorption, distribution, metabolism, elimination (excretion) [Pg.21]

MEEKC Microemulsion electrokinetic chromatography TFA Target factor analysis [Pg.21]

CLOGP Logarithm of the calculated octanol/water partition coefficient (for neutral species) [Pg.21]

A log P Difference between log P in octanol/water and alkane/water log D Logarithm of the distribution coefficient in octanol/water at pH 7.4 log P Logarithm of the partition coefficient in octanol/water (for neutral species) [Pg.21]

Drug Bioavailability Estimation of Solubility, Permeability, Absorption and Bioavailability. Edited by Han van de Waterbeemd, Hans Lennernas and Per Artursson Copyright 2003 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 3-527-30438-X [Pg.21]

See other pages where High-throughput Measurement of log D and pKa is mentioned: [Pg.21]    [Pg.22]    [Pg.26]    [Pg.28]    [Pg.36]    [Pg.600]    [Pg.21]    [Pg.22]    [Pg.26]    [Pg.28]    [Pg.36]    [Pg.600]    [Pg.23]    [Pg.34]   


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D measurements

High-throughput

Measuring log

Measuring pKa

PKa measurement

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