High-dose methylprednisolone in spinal-cord injury

High-dose methylprednisolone in spinal-cord injury 

The results of the second National Acute Spinal Cord Injury Study (NASCIS II) constitutes a major milestone in the search for therapeutic interventions that will interfere significantly with secondary post-traumatic spinal-cord degeneration and thereby ameliorate the devastating neurological consequences of spinal-cord injury [64,65]. In that study, methylprednisolone was demonstrated to improve the 6- and 12-month recovery of spinal-cord injury patients, compared to placebo-treated patients, when administered in an intensive 24-hour intravenous antioxidant dosing regimen beginning within 8 hours after injury. NASCIS II is 

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