Hexamethonium species

The present study consists in examining critically the specific influence of the various organic and inorganic cationic species on the formation and crystallization of ZSM-48 zeolite. Three different reaction systems leading to the formation of ZSM-48 zeolite have been investigated. The first series involved Na+, diamines and Al, the second involved Na+, TMA+ and/or alkylamines and Al, and the last series involved Na+, hexamethonium ions and Al. More particulary, for each organic admixture, we have examined the influence of Na+ and/or Al concentrations on the ZSM-48 (meta)stability and on the nature of the final crystalline product that possibly co-crystallize under these conditions. 

In some species, pharmacological effects other than muscle-relaxation may dominate. Thus, as already seen, the activity of S. erichsonii extracts appears to be due primarily to the presence of diaboline derivatives. Leaf extracts have analgesic properties, while stem-bark extracts have spasmolytic properties and augment the activity of the central nervous system (50). The bark alkaloids of S. glabra are reported to have central rather than peripheral effects (Table 1.4, footnote j). Sublethal doses of aqueous extracts from S. castelnaeana cause hypertension, tachycardia, and slight respiratory stimulation enhancement of the hypertension by atropine and its reduction by hexamethonium (mecamylamine) show that the extract has nicotinic activity. Evidently, the toxicity of the plant must be partly due to the tertiary bases it contains (314). 

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