15-Hexadecynoic acid

J.l Experimental Procedure for Mixed Kolbe Electrolysis — Preparation of 11-Hexadecynoic Acid... 

In a beaker-type cell (Figure 2) equipped with two platinum electrodes (area 10 cm, thickness 0.05 mm, supported on a teflon frame), a solution of 14.3 mmol 5-decynoic acid and 86 mmol methyl sube-rate in 40 mL methanol, neutralized to 5% with KOH, was electrolyzed at 22 C and a current density of 100 mA cm 2, provided from a regulated d.c. power supply, until a pH of 8-9 was reached. After evaporation of the methanol the crude product was refluxed with equimolar amounts of KOH in 100-200 mL methanol for 24 h thereafter the mixture was evaporated to dryness and extracted with petroleum ether. The remaining salt was dissolved in water, acidified with 15% HCl, and continuously extracted with petroleum ether. The precipitated tetradecanoic dicarboxylic acid (72%, m.p. 126 C) was filtered off, and after evaporation of the petroleum ether 8.43 mmol (59%) 11-hexadecynoic acid was isolated by bulb to bulb distillation m.p, (from pentane) 40-41... 

Hexadecynoic acid, H-00215 Hexadexanoic acid 2,3-dihydroxypropyl ester,... 

Hexadecynoic acid, H-20053 3-( 15-Hexadecy ny lidene)dihydro-4-hydroxy-5-methylene-2(3//)-furanone, see M-10004... 

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