Heterogeneous Multifunctional Nanocatalysts

A large fraction of chemical syntheses involve acid- or base-catalyzed processes [44] since acidic and basic functions can activate electrophiles and nucleophiles. 

TABLE 8.8 One-Pot Reaction Cascades Composed of Acid-Catalyzed Hydrolysis and Base-Catalyzed Henry Reaction  

4 PMO-SO3H-NH2+ferf-butyl amine trace trace trace 

SCHEME 8.10 Syntheses of bifunctional mesoporous silica nanoparticles having sulfonic acid groups on the internal surface and organic amine groups on the external surface. 

TABLE 8.9 One-Pot Decacetallization-Nitro Aldol Reaction Cascade  

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In this chapter we present the latest developments in cascade reactions catalyzed by heterogeneous nanocatalysts. Tandan transformations mediated by nanocatalysts can be divided into two types of reactions, involving monofunctional and multifunctional catalyzed processes (Scheme 8.1) [20], We highlight the synthesis approach of these novel nanocatalysts, which have been used successfully to produce active, selective, and dnrable heterogeneous catalysts, and summarize their properties and the cascade reactions which they promote. We then consider potential applications for these new catalysts and look into the future. 

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