Morphine heroin contrasts

These results are in striking contrast to those obtained with the hair from heroin users (Figure 3). Essentially perfect plateau wash kinetics were obtained for 6-MAM, morphine, and codeine. Most important, the amounts of 6-MAM released from the inaccessible domain by digestion easily meets the R sz criterion of heroin use. It should also be mentioned that had the alcohol washes been continued, then the alcohol wash kinetics would have been similar to curve AB in Figure 1. 

Amphetamines increase the concentration of free fatty adds. Morphine increases the activity of amylase and lipase, alanine and aspartate aminotransferases, ALP and the serum bilirubin concentration. The concentrations of gastrin, TSH, and prolactin are also increased. In contrast the concentrations of insulin, norepinephrine, pancreatic polypeptide, and neurotensin are decreased. Heroin increases the plasma concentrations of cholesterol, thyroxine, and potassium. PCO2 is increased but PO2 is decreased. The plasma albumin concentration is also decreased. Cannabis increases the plasma concentrations of sodium, potassium, urea, chloride, and insulin but decreases those of creatinine, glucose, and urate. 

In contrast to morphine, methadone, or heroin, definite withdrawal signs... 

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