Hernandia constituents

In comparison to the Type II alkaloid magnolamine (15), there is extra oxygenation in the only Type Ila alkaloid [vanuatine (255)] at the C(12 ) position. Vanuatine (255)(S,5) is a constituent of Hernandia peltata (Hemandiaceae). 

IDENTIFICATION AND STRUCTURE ELUCIDATION OF REPRESENTATIVE CONSTITUENTS OF HERNANDIA SPECIES... 

Table 2. Known Constituents of Plants in the Genus Hernandia...

Fig. (1). Chemical structures of reported constituents of plants in the genus Hernandia.

CONSTITUENTS OF HERNANDIA SPECIES WITH REPORTED BIOLOGICAL ACTIVITY... 

So far, no potential cancer chemopreventive agent constituent from a Hernandia species has been subjected to biological follow up after the initial in vitro investigation, e.g., by using a mouse mammary organ culture assay [75] or a two-stage mouse skin carcinogenesis test [86]. 

Chen JJ, Ishikawa T, Duh C-Y, Tsai I-L, Chen I-S. New dimeric aporphine alkaloids and cytotoxic constituents of Hernandia nymphaeifolia. Planta Med 1996 62 528-33. 

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