Heparin methyl methacrylate copolymers

Table 9. Thromboresistance of heparin-(methyl methacrylate) copolymers 93 ...

Heparin lithium Methyl methacrylate butadiene styrene terpolymer Styrene-ethylene/butylene-styrene block copolymer... 

Interest continues in the binding of heparin to polymers in an attempt to produce non-thrombogenic surfaces. This has been the aim in the use of glutaralde-hyde-protein complexes as coatings for latex rubber and polyurethanes. Glutaraldehyde has also been used to bind antibodies to partially hydrolysed polyamide surfaces for enzyme-linked radioassay techniques. One of the few examples of direct polymerization (as opposed to surface modification) in an attempt to produce polymers having improved compatibility involves the use of 2-methacryloyloxyethylphosphoryl choline in the formation of homopolymers and copolymers with methyl methacrylate. An isocyanato-urethane methacrylate has been synthesized from 2-hydroxyethyl methacrylate in connection with dental materials research in which the preparation of poly functional monomers for improvement of interfacial bonding with tooth tissue is a topic of some interest. 

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