Heme peptide direct electron transfer

G. Direct Electron Transfer to Heme Peptide and Peroxidase 227... 

Since diamond is inactive for the oxidation and reduction reactions of H2O2, modification of the electrode is required to make diamond suitable for the enzyme-based biosensor application. Tatsuma, et al. [33] reported the use of heme peptide and horseradish peroxidase, types of redox enzymes, based on the direct electron transfer between the diamond electrode and the redox enzyme. Another promising approach is the deposition of metal nanoparticles that have catalytic activity for the H2O2 oxidation- reduction reaction. 

To characterize the electronic coupling in the peroxidase-electrode system, three ET reactions can be distinguished. The first is a one-electron transfer redox process reflecting the conversion between the ferro/ferri redox states, i.e., Fe /Fe . This process is not directly related to the catalytic cycle of peroxidase however, this reaction could be of interest for comparison with similar heterogeneous ET reactions of heme, heme-peptides, cytochrome c, or other heme-con-... 

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