Heck cross-coupling reactions

Scheme 12. Pd(0)-catalyzed Sonogashira and Heck cross-coupling reactions leading to glycoclusters.100...

Meier MAR, FUali M, Gohy J-F, Schubert US (2006) Star-shaped block copolymer stabilized palladium nanoparticles for effident catalytic Heck cross-coupling reactions. J Mater Chem 16 3001-3006... 

Ruhland, B. Bombrun, A. Gallop, M. A. Solid-Phase Synthesis of 4-Ary-lazetidin-2-ones via Suzuki and Heck Cross-Coupling Reactions, J. Org. Chem. 1997, 62, 7820-7826. 

Applications of Suzuki and Heck cross-coupling reactions were adopted by Gallop and coworkers [131] to prepare diverse biaryl- and styryl-substituted (3-lactams on solid support. The catalyst system, [PdCl2(dppf)]-TEA, was found to be efficient to promote C-C bond formation around a (3-lactam template (Schemes 26 and 27). 

Wang, J.-X., Liu, Z., Hu, Y., Wei, B., Bai, L. Microwave-promoted palladium-catalyzed Heck cross-coupling reaction in water. J. Chem. 

The Heck cross coupling reaction has been described with a phosphine-free PVK anchored palla-dium(II) complex as catalyst under aerobic conditions [57]. The Heck cross coupling reaction is shown in Figure 1.9. 

Islam M, Mondal P, Roy AS, Tuhina K. Use of a recyclable poly(n-vinyl carbazole) pal-ladium(n) complex catalyst heck cross-coupling reaction under phosphine-firee and aerobic conditions. Transition Met Chem 2010 35(4) 491-9. 

Crestey, R, Collot, V, Stiebing, S. and Rault, S. (2006) Synthesis of new dehydro 2-azahyptophans and derivatives via Heck cross-coupling reactions of 3-iodoindazoles with methyl 2-(acetylamino)acrylate. Synthesis, 3506-14. 

Fu, X., Zhang, S., Yin, J. et al. (2002) First examples of a tosylate in the palladium-catalyzed Heck cross coupling reaction. Tetrahedron Lett., 43, 573-6. 

One-Pot Sequential Mizoroki-Heck/Cross-Coupling Reaction. ( )-4-[2-(4-Acetyl-phenyl)-l-butylethenyl]benzoic Acid Ethyl Ester (171)... 

Aromatic carboxylic anhydrides have been found to be suitable substrates as aryl sources in the Pd-mediated decarboxylative Mizoroki-Heck cross-coupling reaction (Scheme 22.26) [38]. Olefins with electron-withdrawing groups generally give high yields of the (ii)-P-arylated products. With terminal olefins, a very rapid isomerization occurs and the arylated products are obtained as a mixture of isomers. 

Gao, X., Takeda, K., Zhu, Y., Nakanishi, K., and Shimada, T. (2014) A new hierarchically porous Pd HSQ monolithic catalyst for Mizoroki-Heck cross-coupling reaction. JVew /. Chem., 38, 1144-1149. 

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