Headspace sampling techniques disadvantages

Despite the utility of these techniques, a distinct disadvantage is that very low concentration components may be masked by higher concentration interferants in such cases, devices based on thermal desorption (absorbent packing, static headspace sampling, cryogenic trapping) may prove useful. 

After extraction of the fresh samples of cherries, 35 volatiles were identified by the GC-MS analysis of the flavor extract. The main components of the flavor extracts were hexanal, 3-methyl butanol, limonene, /> nn5-2-hexenal, 1-hexanol, cw-3-hexen-l-ol, tram-3-hexen-l-ol, /ranj -2-hexen-l-ol, linalool, benzaldehyde, 1-octanol, benzyl acetate, benzyl alcohol, and a-terpineol. Due to the nature of the static vacuum extraction technique and the use of a high boiling solvent (iso-octane), compounds more volatile than hexanal were lost during concentration of the solvent extract in a rotary evaporator. This is one of the disadvantages of the static vacuum SDE technique and alternative methods for the analysis of highly volatile chiral compounds need to be used ( e.g., dynamic headspace followed by MDGC). 

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