Hallucinogens major groups

Clinical Manual of Addiction Psychopharmacology Table 6-1 - Major groups of hallucinogens... 

The major difference between the principal members of this group of hallucinogens is their potency. In doses of 1 jtg/kg, LSD is roughly equivalent to... 

Compounds such as LSD or the beta-carbolines do not possess a primary amino group, are not rapidly metabolized in comparison to, for example, tryptamine, and enter the brain readily certain substituent groups can alter this situation. Members of the phenylalkylamine and indolealkylamine families of hallucinogens can produce similar effects in animals but may be capable of producing distinctive effects in man. As yet, there is no satisfactory and comprehensive structure-activity relationship that encompasses both major classes of compounds. This may be due in part to unique metabolic and distributional characteristics associated with the individual ring systems. 

Each year, the National Household Survey on Drug Abuse (NHSDA)—the United States Department of Health and Human Services—collects statistical data on five drug groups marijuana and hashish psychotherapeutic drugs cocaine and crack hallucinogens and inhalants. Psychotherapeutic drugs include stimulants, sedatives, tranquilizers, and pain relievers. Meperidine and other opioids constitute the majority of the pain relievers in that group. 

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