Hallucinogens dependence potential

Pentazocine, although two to three times weaker as an analgetic than morphine, became useful because of its extremely low dependence potential. It does, however, share some of morphine s undesirable side effects, particularly respiratory embarrassment in the upper therapeutic dosage ranges. At single doses of 60 mg or more the dysphoric and hallucinogenic effects first noticed with nalorphine also become apparent with pentazocine. These are reversible with naloxone (but not nalorphine). 

Lobeline has been reported as a useful agent to treat dependency on drugs such as cocaine, amphetamine, caffeine, pheny Icy dine, opiates, barbiturates, benzodiazepines, cannabinoids, hallucinogens, alcohol, and, especially, nicotine. Dwoskin [55] described a novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse. 

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