Gynaminic acid

Subsequently, a number of other compounds isolated from natural products were related to neuraminic acid by formation, from them, of its mono-methoxy derivative. These included prehemataminic acid from erythrocytes, gynaminic acid from human milk and meconium, lactaminic acid... 

Prior to this, its methyl ester (although it was not recognized as such) had been isolated from dialyzed, hydrolyzed cow s colostrum, and designated methoxylactaminic acid. Independently, the free acid was also isolated from both the dialyzable and the non-dialyzable carbohydrate fractions of human milk, and described under the name gynaminic acid. With the development of improved procedures of isolation, particularly recrystallization from acetic acid and water to obtain the alkyl-free acids, it was shown that gynaminic, lactaminic, and ovine sialic acids are identical with W-acetylneuraminic acid. The final identification was made by comparison of their infrared absorption spectra and x-ray powder diffraction patterns, which were respectively identical. 

Acetylamino)-3,5-dideoxy-D-g yceco-D-gaXa.ci.o-2-nonulosonic acid, 9CI. O-Sialic acid. Aceneuramic acid, INN. Lactaminic acid. Gynaminic acid. Serolactaminic acid. KI 111. NANA. NeuSAc. NeuSNAc [131-48-6]... 

An A-acetylneuraminic acid has been isolated from bovine submaxillary mucin and the urinary glycoprotein (urinary mucoprotein of Tamm and Horsfall) following the enzymic action of the influenza virus on the glycoproteins 108), Gynaminic acid, from milk and meconium appear to be identical to the A-acetylneuraminic acid (sialic acid ) from sheep submaxillary gland and different from that from bovine submaxillary glands and lactaminic acid from bovine colostrum 102b, 109),... 

Zilliken, F., Bran, G. A., and Gyorgi, P., 1956, Gynaminic acid and other naturally occurring forms of N-acetylneuraminic acid. Arch. Biochem. Biophys. 63 394-402. 

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