Growth rates of cells

The growth rate of cells is taken proportional to the cell... 

The growth rate of cells is taken proportional to the cell concentration, x, and to an empirical form of the dependence on the concentration, p, of the nutrient. That empirical form was assumed by Monod (1942) to be the same as in the Michaelis-Mewnten model for enzyme kinetics. This makes the rate of cell growth,... 

Figure 7. Membrane-bound CSF-1 on its own induces high self-renewal response of primitive Lin Sea cells. Membrane-bound CSF-1 can stimulate very early cells. Lin Sea-1 cells were cocultivated on MMCE cells ectopically expressing different CSF-1 isoforms as indicated. Increase of Lin Sea-1 cells on MSS stromal cells was set to 100% at each time point. Proliferation of Lin Sca t cells on MMCE feeders was shown as % of Ein Sca-l /MS5 controls. Each point represents the mean SD (three separate experiments). After 3 weeks in coculture a) growth rate of cells stimulated by soluble CSF-1 was profoundly lower than that of cells stimulated by membrane-bound CSF-1 (P<.05).

Group translocation 411 Growth, control of 578 Growth factors 571-576,722 Growth rates of cells 470 Growth regulating hormones 567- 571 GTP (guanosine triphosphate) as coenzyme 719... 

Ornithine decarboxylase is specifically inhibited by the enzyme-activated inhibitor a-difluoromethyl-ornithine, which can cure human infection with Trypanosoma brucei (African sleeping sickness) by interfering with polyamine synthesis.243-2443 In combination with inhibitors of spermidine synthase or S-adenosylmethionine decarboxylase,245 it can reduce polyamine levels and growth rates of cells. Another powerful inhibitor that acts on both ornithine and adenosylmethionine decarboxylases is the hydroxy-lamine derivative l-aminooxy-3-aminopropane 246... 

If liquid medium is inoculated with a seed culture, the cell will start to grow exponentially after the lag phase. The change of the cell concentration in a batch fermenter is equal to the growth rate of cells in it ... 

The generation or consumption terms are defined as follows rx = growth rate of cells rp = production rate of some product rs = consumption rate of substrate... 

AUosteric Sites 470 Box9-B Growth Rates of Cells... 

Microbial contamination can exert numerous effects, and bacterial and yeast contamination will cause nutrient depletion resulting in the death of the cell culture. Although mycoplasma are very fastidious in their growth requirements, contamination with these organisms is known to exert more insidious effects, such as alteration of the growth rate of cells (3), induction of chromosomal aberrations (4), changes in amino acid and nucleic acid metabolism (5,6), and membrane aberrations (7). 

An inspection of Equation (7-86) reveals that the specific growth rate of cells can be ctmtmlfed by the operator by controlling the dilution rate Using Equation (7-52) to substitute for p. in terms of the substrate concer tion and then solving for the steady-state substrate concentration yields... 

The cell concentration is usually expressed by the cell number density Cn (the number of cells per cubic meter of medium), or by the cell mass concentration Cx (the dry weight, in kg, of cells per cubic meter of medium). For any given size and composition of a cell, the cell mass and the cell number per unit volume of medium should be proportional. Such is the case of balanced growth, which is generally attained under some suitable conditions. The growth rate of cells on a dry mass basis, rx (expressed as kg dry cells m-3h-1), is defined by ... 

Thiele modulus for a sphere defined by Equation 20.7. Dimensionless deactivation constant defined as k tp. Specific growth rate of cells, s . ... 

There are other examples of inverse problems in the literature that are worthy of mention. Thus, the determination of growth rates of cells from size distributions during balanced growth of a microbial culture is an interesting example which we treat briefly in the next section. 

Growth Rates of Cells during Balanced Growth... 

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