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Thrombopoietic growth factors

Oprelvekin, human recombinant IL-11, a thrombopoietic growth factor that stimulate stem cells and megakaryocyte progenitor, produced in E. coli... [Pg.518]

Kuter DJ New thrombopoietic growth factors. Blood 2007 109 4607. [PMID 17289815]... [Pg.752]

Interleukin eleven (IL-II) is a thrombopoietic growth factor and has a molecular mass of approximately 19,000 Da, and is nonglycosylated. The polypeptide is 177 amino acids in length. [Pg.343]

Oprelvekin is an interleukin. Interleukin 11 (lL-11) is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation, resulting in increased platelet production. It prevents severe thrombocytopenia and reduces the need for platelet transfusions following myelosuppressive chemotherapy in patients with nonmyeloid malignancies. [Pg.518]

See other pages where Thrombopoietic growth factors is mentioned: [Pg.241]    [Pg.142]    [Pg.481]    [Pg.932]    [Pg.233]   
See also in sourсe #XX -- [ Pg.142 ]



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