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Growth Factors, Oncogenes, and the Cell Cycle

Fig. 15JL Bearing in mind the central role of phosphorylation-dephosphorylation reactions in the control of signaling and in the r Ulation of the cell cycle arxl the role of transcnption factors controlling gene expression in growth and proliferation, it is hardly surprising that cancer-causing oncogenes are mainly cytosolic phosphotyrosine and phosphosenne/threonine protein kinases and phosphatases and transcriptional regulators.

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Cell cycle

Cell factor

Cell growth

Cell growth cells

Cells growth and

Growth The

Growth cycle

Growth factors oncogenes and

Oncogenes

Oncogenes and

Oncogenic

Oncogens

The cell cycle

The growth cycle