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Growth factor receptor trafficking

Resat H, Ewald JA, Dixon DA, Wiley HS. An integrated model 93. of epidermal growth factor receptor trafficking and signal transduction. Biophys. J. 2003 85 730-743. 94. [Pg.2221]

C. Starbuck, D.A. Lauffenburger, Mathematical model for the effects of epidermal growth factor receptor trafficking dynamics on fibroblast proliferation responses, Biotechnol. Prog. 1992, 8, 132-143. [Pg.1078]

Huang F, Khvorova A, Marshall W, Sorkin A. Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J. Biol. Chem. 2004 279 16657-16661. Hinrichsen L, Harborth J, Andrees L, Weber K, Ungewickell EJ. Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells. J. Biol. Chem. 2003 278 45160-45170. Wu AM, Senter PD. Arming antibodies prospects and challenges for immunoconjugates. Nat. Biotechnol. 2005 23 1137-1146. [Pg.393]

Girard, M. and McPherson, P.S. 2008. RME-8 regulates trafficking of the epidermal growth factor receptor. FEBS Letters, 582(6), 961-966. Retrieved from http //www.nchi.nlm.nih.gov/ puhmed/18307993... [Pg.242]

Insulin affects APP metabolism. sAPPp secretion can be regulated by several growth factors that act at receptors with intrinsic tyrosine kinase activity (which includes IRs) (Refolo et al, 1989 Schubert et al., 1989). Gasparini et al. (2001) showed that insulin decreases intracellular levels of Ap and increases extracellular levels of Ap through accelerated PAPP trafficking to the plasma membrane mediated by tyrosine kinase/MAPK pathways. Extracellular Ap can inhibit insulin... [Pg.508]


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Trafficking

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