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Group Sequential Alpha Spending Functions

The original methodology for group sequential designs, and hence interim analyses, required that the number and timing of interim analyses be specified in advance. However, in cases where potentially unfavorable safety data may be emerging, a [Pg.127]

6 Meta-analysis, Group Sequential Study Designs, and other topics [Pg.128]

See other pages where Group Sequential Alpha Spending Functions is mentioned: [Pg.184]    [Pg.127]    [Pg.184]    [Pg.127]    [Pg.298]    [Pg.185]    [Pg.128]    [Pg.262]    [Pg.262]   


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