Group 11 metal-promoted oxidations oxidative biaryl coupling

Group 11 metal-promoted oxidations oxidative biaryl coupling 

CautionI Employ the standard precautions outlined in the introduction to this chapter for this reaction. 

Clean all glassware, syringes, and needles sequentially in soap solution, water, and acetone. Allow the acetone to evaporate and then dry everything in an electric oven (105 0 for at least 1 h. 

Put the copper(ll) nitrate (9.4 g, 0.05 mol), and the magnetic stirrer bar into the round-bottomed flask and add methanol (120 mL). Stir the mixture until all of the solid has dissolved to give a bright blue solution. 

Dissolve 2-naphthol (5.66 g, 0.04 moi) in methanol (100 mL). Add this solution to the reaction mixture to give a dark green solution. Stopper the flask sealing it with one or two wraps of Nesco film or Parafilm. Allow the reaction to stir at room temperature for 1 week.  

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