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Groove in DNA

Non-intercalative groove binding. The drug lies in one of the grooves in DNA, following the helical contour of DNA as it binds. Netropsin and dlstamycin bind in this way. [Pg.766]

Groove in DNA The structures of DNA have grooves between the lines of phosphodiester backbone. In the Watson-Crick model (B-DNA) the major groove is deep and wide and the minor groove is shallow and narrow. Different functional groups on the bases are accessible in the two different grooves of the same DNA molecule. [Pg.772]

Space filling models of DNA reveal two grooves that run the length of the molecule (Figure 23-6b). The major groove is wide and deep and the minor groove is narrow and shallow. These grooves in DNA provide... [Pg.525]

There are two kinds of grooves in DNA helixes, i.e. major and minor grooves, which can interact with metal ions or organic guests. Since these grooves are well-structured... [Pg.17]

See other pages where Groove in DNA is mentioned: [Pg.1197]    [Pg.152]    [Pg.127]    [Pg.199]    [Pg.525]    [Pg.603]    [Pg.281]    [Pg.469]    [Pg.1122]    [Pg.369]    [Pg.384]    [Pg.388]    [Pg.1314]    [Pg.1314]   
See also in sourсe #XX -- [ Pg.772 ]



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Grooves

Grooving

Major groove, in DNA

Minor groove, in DNA

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